Which organ is most likely the source of pain in the lower right quadrant?

• A. Kidney
• B. Appendix
• C. Gallbladder
• D. Sigmoid colon

Answer: (B)

Pain location in the abdomen usually points to the organ in that quadrant. The appendix sits in the lower right quadrant near the ileocecal junction, so inflammation tends to cause pain there. In appendicitis, pain often starts around the belly button and then localizes to the lower right area, with tenderness at McBurney’s point. Among the options, only the appendix is primarily in that region; kidney pain tends to be in the flank or groin, gallbladder pain is in the upper right, and the sigmoid colon is in the lower left. So the appendix best fits the scenario.